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Platelets (PLT)

Blood count (CBC) ·Also called: PLT, thrombocytes, platelet count, thrombocytopenia

What it is

Platelets are produced in the bone marrow and circulate for about a week. When a vessel is injured they stick to the site and to each other, forming the first temporary seal before the clotting proteins reinforce it.

Why your vet measures it

Spontaneous bleeding — pinpoint bruises on the gums or belly, nosebleeds, blood in urine — becomes a risk only when the count falls a long way below normal. Values modestly below the range rarely cause signs, and are often investigated for their cause rather than treated directly.

What a high result can mean

  • A reactive response to inflammation, infection, or recent surgery
  • Iron deficiency
  • Removal of the spleen, or recovery after significant blood loss
  • Rarely, a bone marrow disorder driving genuine overproduction

What a low result can mean

  • Clumping in the sample tube, which the analyser cannot count — the most common cause of a low feline result
  • Immune-mediated destruction, a well-recognised condition in dogs
  • Tick-borne infections such as ehrlichiosis and anaplasmosis
  • Consumption in widespread clotting (DIC), or bleeding from a vascular tumour
  • Bone marrow disease or drug-related suppression

Dogs and cats differ

Feline platelets clump readily, so a low count on a cat's report is routinely rechecked on a smear before anyone acts on it. Cavalier King Charles Spaniels commonly carry an inherited macrothrombocytopenia: fewer but larger platelets, which analysers undercount, in dogs that clot perfectly well.

Questions worth asking your vet

  • Was a blood smear checked for platelet clumping before we act on this?
  • Is my pet's breed known for a benign low platelet count?
  • Are there any signs of bleeding I should be watching for at home?

Related terms

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